

These reduce or stop sneezing, runny noses, and itching. They also help relieve red, itchy, watery eyes. These clear up a stuffy (congested) nose. Over-the-counter medicines used to control the symptoms of allergies, including allergic rhinitis, include: Talk with a pharmacist if you have any questions. It is usually best to take only single-ingredient allergy or cold preparations, instead of those containing many active ingredients. Read and follow all instructions on the label.

These medicines work well but can have side effects. Our publishing portfolio includes journals and online resources, including Journal of Endocrinology, Endocrine-Related Cancer, Endocrine Connections, Bone Abstracts and Endocrinology, Diabetes & Metabolism Case Reports.Many over-the-counter medicines are available to control symptoms of allergies, including allergic rhinitis. Bioscientifica collaborates with learned societies worldwide to develop new and existing quality products that meet the ever-changing needs of the biomedical community. Reproduction is published by Bioscientifica, an innovative and agile publisher. The review “ Potential deleterious effects of anti-histamines on male reproductive function” was published in Reproduction on 9 March 2018. In future work, the research group is planning on evaluating the role of histamines in the biology of testicular cell tumours. Dr Mondillo adds: “The data compiled in this review indicates the crucial involvement of histamine in orchestrating testicular functions, but even so there is still much to learn about the implicated mechanisms”. This can then lead to developing novel treatments to relieve allergy symptoms without compromising fertility”, Dr Carolina Mondillo, one of the authors involved in the study, said.Īlthough the research reviewed was mostly conducted in animals, and human studies are still limited, there is evidence that histamine plays a role in the male reproductive system. “More large-scale trials are needed to evaluate the possible negative effects of antihistamine on reproductive and sexual health. The review concludes that anti-histamines are likely to affect the production of male sexual hormones in the testicles, which can lead to altered morphology and decreased motility of sperm, as well as a lower sperm count. A number of studies reported adverse effects of anti-histamine on normal testicular function. In this review, researchers at the Instituto de Biologia y Medicina Experimental (YBIME-CONICET), Argentina, looked at a mix of small and large scale animal research studies, conducted in the topic of histamines and fertility, conducted over the last 40 years. This suggests that blocking histamine activity to treat allergy symptoms may lead to undesirable side effects. However, previous research shows that histamines are also involved in other bodily processes unrelated to allergic reactions, including sleep-wake regulation, sexual behaviour, and fertility. Although the reasons for this are unclear, this phenomenon is leading to an increased use of allergy drugs like anti-histamines, both over-the-counter and prescribed.
OVER THE COUNTER ANTIHISTAMINE SKIN
Antihistamines are the most common treatment used to alleviate or prevent these symptoms, including a runny or blocked nose, wheezing, sneezing or skin rashes.Īllergies in the industrialised world are on the rise. Symptoms of common mild allergies, such as hay fever, are mediated by histamine, a molecule produced by the body in response to certain conditions where the immune system detects a potential threat. Researchers highlight that patients should be cautioned against antihistamine overuse, and stress the need to further evaluate these negative effects in bigger clinical studies.

Over-the-counter allergy drugs could have negative long-term side effects for male fertility, a review, published in the journal Reproduction, suggests. Over-the-counter antihistamines linked to impaired fertility in men
